FSL-1

• Target:

  TLR|||Antibiotic

• Related Pathways:

  Microbiology/Virology|||Immunology/Inflammation

• Bioactivity:

  TLR2/6 agonist (also a putative TLR10 ligand) . Activates NF-?B. Induces pro-inflammatory cytokines including IL-8, IL-1?, CCL20 and TNF-? in vitro. Synergizes with IFN? to induce CXCL10 release from melanoma cells.

• Smiles:

  C ([C@H] (CC1=CN=CN1) NC ([C@@H] (NC (=O) [C@H]2N (C ([C@@H] (NC (CNC ([C@H] (CSCC (OC (CCCCCCCCCCCCCCC) =O) COC (CCCCCCCCCCCCCCC) =O) N) =O) =O) CC (O) =O) =O) CCC2) CCCCN) =O) (=O) N3[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@@H] (CC4=CC=CC=C4) C (O) =O) =O) CO) =O) CCCCN) =O) CCC3

• Molecular Formula:

  C84H140N14O18S

• Molecular Weight:

  1666.16

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  322455-70-9