FSL-1

• Target:

  TLR|||Antibiotic

• Related Pathways:

  Microbiology/Virology|||Immunology/Inflammation

• Bioactivity:

  TLR2/6 agonist (also a putative TLR10 ligand) . Activates NF-?B. Induces pro-inflammatory cytokines including IL-8, IL-1?, CCL20 and TNF-? in vitro. Synergizes with IFN? to induce CXCL10 release from melanoma cells.

• Smiles:

  C([C@H](CC1=CN=CN1)NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC(CNC([C@H](CSCC(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)N)=O)=O)CC(O)=O)=O)CCC2)CCCCN)=O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)CO)=O)CCCCN)=O)CCC3

• Molecular Formula:

  C84H140N14O18S

• Molecular Weight:

  1666.16

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  322455-70-9