M 1145 acetate

• Target:

  Neuropeptide Y Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein

• Purity:

  0.991

• Bioactivity:

  M1145 acetate, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 acetate shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM) . M1145 acetate has an additive effect on the signal transduction of galanin[1].

• Smiles:

  CC (O) =O.C[C@@H] (C (N) =O) NC ([C@H] (CC (C) C) NC ([C@H] (C) NC ([C@H] (CC (C) C) NC ([C@H] (C) NC ([C@H]1N (C ([C@H]2N (C ([C@H]3N (C ([C@H] (CC (C) C) NC ([C@H] (C (C) C) NC ([C@H]4N (C (CNC ([C@H] (CC (C) C) NC ([C@H] (CC (C) C) NC ([C@H] (CC5=CC=C (O) C=C5) NC (CNC ([C@H] (C) NC ([C@H] (CO) NC ([C@H] (CC (N) =O) NC ([C@H] (CC (C) C) NC ([C@H] ([C@H] (O) C) NC ([C@H] (CC6=CNC7=C6C=CC=C7) NC ([C@H] (CC (N) =O) NC (CNC ([C@H] (CCCNC (N) =N) NC (CNC ([C@H] (CCCNC (N) =N) N) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) CCC4) =O) =O) =O) CCC3) =O) CCC2) =O) CCC1) =O) =O) =O) =O) =O

• Molecular Formula:

  C130H209N37O34

• Molecular Weight:

  2834.28

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C