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M 1145 acetate

CAT: 0931-TP1991L-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TP1991L-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Neuropeptide Y Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.991
Bioactivity
M1145 acetate, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a Ki of 6.55 nM. M1145 acetate shows more than 90-fold higher affinity for GAL2 over GAL1 (Ki=587 nM) and a 76-fold higher affinity over GalR3 (Ki=497 nM) . M1145 acetate has an additive effect on the signal transduction of galanin[1].
Smiles
CC(O)=O.C[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H]1N(C([C@H]2N(C([C@H]3N(C([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H]4N(C(CNC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC5=CC=C(O)C=C5)NC(CNC([C@H](C)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H](CC6=CNC7=C6C=CC=C7)NC([C@H](CC(N)=O)NC(CNC([C@H](CCCNC(N)=N)NC(CNC([C@H](CCCNC(N)=N)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC4)=O)=O)=O)CCC3)=O)CCC2)=O)CCC1)=O)=O)=O)=O)=O
Molecular Formula
C130H209N37O34
Molecular Weight
2834.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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