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CAT: 0931-TP1972Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TP1972Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively) . Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 μM) . Inhibits fast inactivation on all channels. Increases peak currents at all voltages and stimulates a persistent Na+ current at hNav1.7 channel. Increases hyperpolarization at Nav1.4 and Nav1.6 channels. Induces spontaneous pain in vivo.
Molecular Formula
C308H466N90O95S8
Molecular Weight
7206.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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