Hemokinin 1, human

• Target :

  Neurokinin receptor

• Related Pathways :

  Neuroscience|||GPCR/G Protein

• Bioactivity :

  Endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively) . Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo.

• Smiles :

  [C@H](CC1=CC=CC=C1)(C(N[C@@H](CC2=CC=CC=C2)C(NCC(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H]([C@@H](C)O)N)=O)=O)CCCCN)=O)C)=O)CO)=O)CCC(N)=O)=O

• Molecular Formula :

  C54H84N14O14S

• Molecular Weight :

  1185.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  491851-53-7