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NoxA1ds

CAT: 0931-TP1886-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-TP1886-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1435893-78-9
Target
NADPH
Related Pathways
Metabolism
Bioactivity
Potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 = 20 nM) . Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. Cell permeable.
Smiles
C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@@H](C)C)C(N)=O)=O)CCCCN)=O)C)=O)CCCCN)=O)=O)CC(C)C)=O)C)=O)CC(O)=O)=O)C(C)C)(=O)[C@H]1N(C([C@H](CCC(O)=O)N)=O)CCC1
Molecular Formula
C50H88N14O15
Molecular Weight
1125.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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