Apamin

• Target :

  Potassium Channel

• Related Pathways :

  Membrane transporter/Ion channel

• Bioactivity :

  Apamin (Apamine) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom) that selectively blocks Ca2+-activated K+ (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity. This component of bee venom is strongly basic in nature.

• Smiles :

  CC(C)CC1NC(=O)C(C)NC(=O)C(NC(=O)C(CCC(O)=O)NC(=O)C2CCCN2C(=O)C(C)NC(=O)C(CCCCN)NC(=O)C2CSSCC(NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCNC(N)=N)NC(=O)C(C)NC(=O)C(CSSCC(N)C(=O)NC(CC(N)=O)C(=O)N2)NC1=O)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(N)=O)C(=O)NC(Cc1c[nH]cn1)C(N)=O)C(C)O

• Molecular Formula :

  C79H131N31O24S4

• Molecular Weight :

  2027.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  24345-16-2