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Sincalide ammonium

CAT: 0931-TP1198-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TP1198-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
70706-98-8
Target
PI3K, Cholecystokinin Receptor, Apoptosis, Akt
Related Pathways
PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, GPCR/G Protein, Apoptosis
Purity
0.9846
Bioactivity
Sincalide ammonium (CCK-8 ammonium) is a potent analog of the amino acid peptide hormone cholecystokinin (CCK), an active fragment that retains much of the biological activity of CCK.Sincalide ammonium promotes bile secretion, causes gallbladder contractions and relaxes the sphincter of Oddi, thereby facilitating bile drainage into the duodenum. Sincalide ammonium promotes bile secretion, contraction of the gallbladder and relaxation of the sphincter of Oddi, thereby facilitating the drainage of bile into the duodenum.Sincalide ammonium can be injected to promote gallbladder contraction, and is commonly used as an adjunct in the diagnosis of gallbladder and pancreatic diseases and in cholecystography.
Smiles
N.CSCC[C@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Molecular Formula
C49H65N11O16S3
Molecular Weight
1160.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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