TAK-448

• Target :

  Kisspeptin

• Related Pathways :

  GPCR/G Protein

• Bioactivity :

  TAK-448 (MVT-602), a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM, has been studied in trials for the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.

• Smiles :

  C([C@H](NC([C@@H](NC([C@@H](NC(NNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC(=O)[C@H]2N(C([C@@H](CC3=CC=C(O)C=C3)NC(C)=O)=O)C[C@H](O)C2)CC(N)=O)=O)[C@@H](C)O)=O)=O)=O)CC(C)C)=O)CCCNC(NC)=N)=O)C(N)=O)C=4C=5C(NC4)=CC=CC5

• Molecular Formula :

  C58H80N16O14

• Molecular Weight :

  1225.36

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1234319-68-6