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Angoline

CAT: 0931-TN6739-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN6739-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
21080-31-9
Target
Interleukin, STAT, IL Receptor
Related Pathways
JAK/STAT signaling, Immunology/Inflammation, Stem Cells
Purity
0.9996
Bioactivity
Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor (IC50 : 11.56 μM) . It inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.
Smiles
COC1N(C)c2c(ccc3cc4OCOc4cc23)-c2ccc(OC)c(OC)c12
Molecular Formula
C22H21NO5
Molecular Weight
379.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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