Angoline

• Target :

  Interleukin|||STAT|||IL Receptor

• Related Pathways :

  JAK/STAT signaling|||Immunology/Inflammation|||Stem Cells

• Purity :

  0.9996

• Bioactivity :

  Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor (IC50 : 11.56 ?M) . It inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.

• Smiles :

  COC1N(C)c2c(ccc3cc4OCOc4cc23)-c2ccc(OC)c(OC)c12

• Molecular Formula :

  C22H21NO5

• Molecular Weight :

  379.41

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  21080-31-9