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5,6-Benzoflavone

CAT: 0931-TN6694-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-TN6694-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
6051-87-2
Target
Apoptosis, Antioxidant, Aryl Hydrocarbon Receptor
Related Pathways
Apoptosis, Immunology/Inflammation, Oxidation-Reduction
Purity
0.9988
Bioactivity
5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (β-Naphthoflavone) possesses anti-inflammatory and antioxidant activities, inhibits LPS-induced inflammation through the AKT/Nrf-2/HO-1-NF-kappaB signaling axis, inhibits TNF-α-induced ICAM-1 and VCAM-1 expression, which can be used to study neurodegenerative diseases.
Smiles
O=c1cc(oc2ccc3ccccc3c12)-c1ccccc1
Molecular Formula
C19H12O2
Molecular Weight
272.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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