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Trachelogenin

CAT: 0931-TN6508-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN6508-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
34209-69-3
Target
Virus Protease, Wnt/beta-catenin, c-Myc, HCV Protease
Related Pathways
Stem Cells, Cytoskeletal Signaling, Cell Cycle/Checkpoint, Microbiology/Virology, Proteases/Proteasome
Purity
0.9987
Bioactivity
Trachelogenin ((-) -Trachelogenin), isolated from Combretum fruticosum, is an HCV entry inhibitor with anti-proliferative effects. Its mechanism is related to affecting the phosphorylation of key proteins such as β-Catenin, c-Myc and GSK3 in the β-Catenin signaling pathway. chemical and concentration-dependent. Trachelogenin has antiviral, anti-inflammatory and analgesic activities with IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively.
Smiles
COc1cc(C[C@]2(O)[C@@H](Cc3ccc(OC)c(OC)c3)COC2=O)ccc1O
Molecular Formula
C21H24O7
Molecular Weight
388.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C