Alisol B acetate

• Target:

  Caspase|||Apoptosis|||Akt|||PI3K

• Related Pathways:

  Proteases/Proteasome|||Cytoskeletal Signaling|||Apoptosis|||PI3K/Akt/mTOR signaling

• Bioactivity:

  Alisol B acetate can induce Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells, the Bax activation and translocation from the cytosol to nucleus might be a crucial response to the apoptotic effect. Alisol B acetate exhibits an antiproliferative effect in SGC7901 cells by inducing apoptosis, apoptosis of SGC7901 cells involves mitochondria-caspase and PI3K/Akt dependent pathways.

• Smiles:

  CC(C)C(=O)[C@H](C[C@@H](C)C1=C2C[C@H](O)[C@H]3[C@@]4(C)CCC(=O)C(C)(C)[C@@H]4CC[C@]3(C)[C@@]2(C)CC1)OC(C)=O

• Molecular Formula:

  C32H50O5

• Molecular Weight:

  514.74

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  19865-76-0