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Toddaculin

CAT: 0931-TN5888-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-TN5888-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
4335-12-0
Target
Apoptosis, Others
Related Pathways
Apoptosis, Others
Purity
0.9991
Bioactivity
Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1/2, and p38 MAPK signaling pathways, but can induce differentiation and mineralization of osteoblasts by regulating differentiation factors. Toddaculine also may serve as a pharmacological prototype for the development of novel anti-leukemic agents, it displays a dual effect as a cell differentiating agent and apoptosis inducer in U-937 cells.
Smiles
COc1cc2oc(=O)ccc2c(OC)c1CC=C(C)C
Molecular Formula
C16H18O4
Molecular Weight
274.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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