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Bonducellin

CAT: 0931-TN5474Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN5474Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
83162-84-9
Target
Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF) -alpha and interleukin (IL) -12. Bonducellin shows weak antimalarial activity against Plasmodium falciparum with the IC50 value of 26 uM; it also shows weak antiproliferative against A2780 human ovarian cancer cell line , with the IC50 value of 10.6 uM. Bonducellin shows modulation in the MIC of EtBr by eight fold at a concentration of 62.5 mg/L and also shows significant efflux pump inhibitory activity.
Smiles
COc1ccc(\C=C2/COc3cc(O)ccc3C2=O)cc1
Molecular Formula
C17H14O4
Molecular Weight
282.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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