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Vitexilactone

CAT: 0931-TN5243Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN5243Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
61263-49-8
Target
Antifection, NADPH-oxidase, Apoptosis, HIV Protease, Antibacterial
Related Pathways
Immunology/Inflammation, Proteases/Proteasome, Apoptosis, Microbiology/Virology
Bioactivity
Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse transcriptase. It has trypanocidal activity, the minimum lethal concentration against epimastigotes of Trypanosoma cruzi is 66 microM.Vitexilactone is one anticancer component of Vitex trifolia L., which exerts its anti-proliferative effect on cancer cells through inducing apoptosis and inhibiting the cell cycle.
Smiles
C[C@@H]1C[C@@H](OC(C)=O)C2C(C)(C)CCC[C@]2(C)[C@@]1(O)CCC1=CC(=O)OC1
Molecular Formula
C22H34O5
Molecular Weight
378.509
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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