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Taspine

CAT: 0931-TN5100Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN5100Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
602-07-3
Target
P2X Receptor, Bcl-2 Family, VEGFR, Akt, EGFR, MAPK, ERK
Related Pathways
MAPK, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Neuroscience, JAK/STAT signaling, Membrane transporter/Ion channel, Apoptosis, Angiogenesis, Cytoskeletal Signaling
Bioactivity
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful angiogenesis activity. Taspine exhibits a dose-related cicatrizant effect and an ED50 of 0.375 mg/kg.
Smiles
COc1ccc2c3c1oc(=O)c1c(CCN(C)C)cc(OC)c(oc2=O)c31
Molecular Formula
C20H19NO6
Molecular Weight
369.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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