Tagitinin A

• Target:

  Antifection|||PPAR

• Related Pathways:

  Microbiology/Virology|||Metabolism|||DNA Damage/DNA Repair

• Bioactivity:

  Tagitinin A is a naturally occurring sesquiterpene lactone compound that acts as a dual agonist of peroxisome proliferator-activated receptor ?/? (PPAR?/PPAR?) and exerts antihyperglycemic and antihyperlipidemic effects in diabetes research.Tagitinin A is able to bind directly to the ligand-binding domain of PPAR? (IC50=55 ?M), and also stimulates the PPAR Tagitinin A can directly bind to the PPAR? ligand binding domain (IC50=55 ?M) and also stimulate the PPAR?-dependent activation of the SULT2A1 gene promoter. As a phytotoxin, Tagitinin A significantly inhibited the growth of wheat germ sheath.

• Smiles:

  O(C(C(C)C)=O)[C@H]1[C@@]2([C@@](C[C@H](C)[C@@]3(O)O[C@](C)(C1)[C@H](O)C3)(OC(=O)C2=C)[H])[H]

• Molecular Formula:

  C19H28O7

• Molecular Weight:

  368.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  59979-61-2