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Skullcapflavone I

CAT: 0931-TN5033Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN5033Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
41060-16-6
Target
Prostaglandin Receptor, IL Receptor, Caspase, MicroRNA, Serine Protease
Related Pathways
Proteases/Proteasome, Chromatin/Epigenetic, Immunology/Inflammation, GPCR/G Protein, Apoptosis
Bioactivity
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE (2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I selectively induces apoptosis in T-HSC/Cl-6 cells via caspase-3 and caspase-9 activation.
Smiles
COc1cc(O)c2c(oc(cc2=O)-c2ccccc2O)c1OC
Molecular Formula
C17H14O6
Molecular Weight
314.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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TBW00608Skullcapflavone I
BUP03652-01Skullcapflavone II

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