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Semialactone

CAT: 0931-TN4987Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN4987Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
366450-46-6
Target
Others
Related Pathways
Others
Bioactivity
Semialactone shows inhibitory activities on human acyl-CoA:cholesterol acyltransferase (hACAT) 1 with IC50 values of 79.1 uM and on human hACAT2 with IC50 values of 76.9 uM, it may be effective in the prevention and treatment of hypercholesterolemia or atherosclerosis via inhibitory effect on hACAT.
Smiles
C\C1=C\C[C@H](O)C(=C)[C@H]2CC[C@]3(COC1=O)[C@@H]2CC[C@H]1[C@@]3(C)CCC2C(C)(C)[C@@]3(O)CC[C@]12CO3
Molecular Formula
C30H44O4
Molecular Weight
468.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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