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Scandoside

CAT: 0931-TN4956-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-TN4956-01Size:1 mL - 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
18842-99-4
Target
NF-κB, MAPK
Related Pathways
NF-κB, MAPK
Purity
0.9893
Bioactivity
Scandoside, a cyclic enolide that can be isolated from Haemophilus difficile, exhibits anti-inflammatory activity, inhibits the expression levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), TNF-α, and IL-6 messenger RNA (mRNA), and inhibits the nuclear transcription factor, kappa-B alpaha (IκB-α), p38, extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) inhibitor phosphorylation.
Smiles
O([C@H]1[C@]2([C@@](C(C(O)=O)=CO1)([C@H](O)C=C2CO)[H])[H])[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O
Molecular Formula
C16H22O11
Molecular Weight
390.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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