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Murrangatin

CAT: 0931-TN4592Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN4592Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
37126-91-3
Target
Prostaglandin Receptor, COX, IL Receptor, TNF
Related Pathways
Apoptosis, Neuroscience, GPCR/G Protein, Immunology/Inflammation
Bioactivity
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100. Murrangatin exhibits antibacterial activity against P. gingivalis (ATCC 33277) . Murrangatin also shows soluble epoxide hydrolase inhibitory activity with IC50 values 13.9±6.5uM. Murrangatin and murracarpin may be a new backbone for developing inhibitors of cyclooxygenase 2, they show chondroprotective activity by downregulation of interleukin-1β, tumor necrosis factorα, prostaglandins E2, and matrix metalloproteinases -13, and both of them may be a new backbone for developing inhibitors of cyclooxygenase 2.
Smiles
COc1ccc2ccc(=O)oc2c1[C@@H](O)[C@@H](O)C(C)=C
Molecular Formula
C15H16O5
Molecular Weight
276.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-N3233Murrangatin
BCA65059-01Murrangatin diacetate

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