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Morolic acid

CAT: 0931-TN4584Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN4584Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
559-68-2
Target
COX, IL Receptor, HIV Protease
Related Pathways
Immunology/Inflammation, Microbiology/Virology, Neuroscience, Proteases/Proteasome
Bioactivity
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Morolic acid exhibits pronounced radical scavenging activity against the stable 2,2-diphenyl-1-picrylhydrazyl radical and is a potent inhibitor of neutrophil elastase and cyclooxygenase-1 and -2 in vitro. Morolic acid has anti- inflammatory activity, it can inhibit leukotriene B4 production in rat polymorphonuclear leukocytes stimulated with calcium ionophore A 23187. Morolic acid exhibits promising anti-HIV activity, it also exhibits moderate inhibitory activity against glycogen phosphorylase.
Smiles
CC1(C)CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)C2=C1)C(O)=O
Molecular Formula
C30H48O3
Molecular Weight
456.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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