Jolkinolide A

• Target:

  STAT|||mTOR|||VEGFR|||Akt|||Apoptosis

• Related Pathways:

  Stem Cells|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Apoptosis|||JAK/STAT signaling|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors

• Bioactivity:

  Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly inhibited the proliferation and migration of HUVECs.

• Smiles:

  CC1=C2[C@H]3O[C@]33CC[C@@H]4C(C)(C)CCC[C@@]4(C)[C@@H]3C=C2OC1=O

• Molecular Formula:

  C20H26O3

• Molecular Weight:

  314.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  37905-07-0