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Jolkinolide A

CAT: 0931-TN4356Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN4356Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
37905-07-0
Target
STAT, mTOR, VEGFR, Akt, Apoptosis
Related Pathways
Stem Cells, PI3K/Akt/mTOR signaling, Angiogenesis, Apoptosis, JAK/STAT signaling, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors
Bioactivity
Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly inhibited the proliferation and migration of HUVECs.
Smiles
CC1=C2[C@H]3O[C@]33CC[C@@H]4C(C)(C)CCC[C@@]4(C)[C@@H]3C=C2OC1=O
Molecular Formula
C20H26O3
Molecular Weight
314.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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