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Isodunnianol

CAT: 0931-TN4286Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN4286Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
139726-30-0
Target
Autophagy, AChR, NF-κB, NOS, ROS
Related Pathways
NF-κB, Immunology/Inflammation, Autophagy, Neuroscience
Bioactivity
Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0.1 to 10 uM in the primary cultured rat cortical neurons. Isodunnianol, dunnianol, and Macranthol have anti-inflammatory activity, they can increase NAG-1 (multiple targets related to inflammation) activity 1.5 -3.0 fold and decrease cellular oxidative stress by 40-65%, they show substantial activity against iNOS.
Smiles
Oc1ccc(CC=C)cc1-c1cc(CC=C)cc(Oc2ccc(CC=C)cc2)c1O
Molecular Formula
C27H26O3
Molecular Weight
398.502
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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