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Hirsutenone

CAT: 0931-TN4213Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN4213Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
41137-87-5
Target
P53, PI3K, EGFR, Autophagy, Antifection, mTOR, ERK, IL Receptor, Akt, NF-κB
Related Pathways
Cytoskeletal Signaling, Autophagy, Immunology/Inflammation, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors, Microbiology/Virology, PI3K/Akt/mTOR signaling, NF-κB, JAK/STAT signaling, MAPK
Bioactivity
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation.Hirsutenone exhibits anti-cancer, and anti-filarial effects, it may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity.
Smiles
Oc1ccc(CC\C=C\C(=O)CCc2ccc(O)c(O)c2)cc1O
Molecular Formula
C19H20O5
Molecular Weight
328.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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