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Guajadial B

CAT: 0931-TN4172Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN4172Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1414455-03-0
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Bioactivity
Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. Guajadial B shows cytotoxicities against five human cancer cell lines, it is the most effective having an IC50 value of 150 nM toward A549 cells.
Smiles
C\C1=C/CC(C)(C)\C=C\C[C@@]2(C)Oc3c(C=O)c(O)c(C=O)c(O)c3[C@H]([C@@H]2CC1)c1ccccc1
Molecular Formula
C30H34O5
Molecular Weight
474.597
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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