Products for Research Use Only

Glochidiol

CAT: 0931-TN4140Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN4140Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
6610-56-6
Target
Others, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
Glochidiol exhibits strong inhibitory effects against all three human tumor cell lines (MCF-7, NCI-H-460 and SF-268), it exerts its antiproliferative activity through the involvement of apoptosis. It exhibits a strong inhibitory effect on mouse skin tumor promotion in an in vivo mouse two-stage carcinogenesis test. Glochidiol (IC50 = 290 mol ratio/32 pmol TPA) also shows inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol 13-acetate (TPA) .
Smiles
CC(=C)[C@@H]1CC[C@]2(C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)[C@H](O)C[C@@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12
Molecular Formula
C30H50O2
Molecular Weight
442.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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