Danshenol A

• Target:

  ROS|||Reactive Oxygen Species|||Reductase

• Related Pathways:

  Metabolism|||NF-?B|||Endocrinology/Hormones|||Immunology/Inflammation

• Bioactivity:

  Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A also has antitumor activity in T-24, QGY, K562, Me180 and BIU87 cell lines, shows inhibited growth of K562 (IC50 = 0.53 ?g/mL), T-24 (IC50 = 7.94 ?g/mL), QGY (IC50 = 4.65 ?g/mL) and Me180 (IC50 = 6.89 ?g/mL) cell lines.

• Smiles:

  C[C@H]1COC2=C1C(=O)[C@](O)(CC(C)=O)c1c2ccc2c(C)cccc12

• Molecular Formula:

  C21H20O4

• Molecular Weight:

  336.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  189308-08-5