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Cimiside E

CAT: 0931-TN3655-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN3655-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
154822-57-8
Target
TNF, ERK, Caspase, Akt, PI3K, ROS, PKC, PPAR
Related Pathways
Cytoskeletal Signaling, Metabolism, MAPK, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, Proteases/Proteasome, DNA Damage/DNA Repair, Apoptosis, Immunology/Inflammation
Bioactivity
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may be an effective chemopreventive agent against cancer, it arrests cell cycle and induces cell apoptosis in gastric cancer cells.
Smiles
[H][C@]12[C@H](C)C[C@H]3O[C@@]1(O[C@H]3C(C)=C)[C@H](O)[C@@]1(C)[C@]3([H])CC[C@]4([H])[C@]5(C[C@@]35CC[C@]21C)CC[C@H](O[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)C4(C)C
Molecular Formula
C35H54O8
Molecular Weight
602.809
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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