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(S) - (-) -Canadine

CAT: 0931-TN3574-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN3574-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
5096-57-1
Target
ATPase, Dopamine Receptor, 5-HT Receptor
Related Pathways
GPCR/G Protein, Membrane transporter/Ion channel, Neuroscience
Bioactivity
(S) - (-) -Canadine (tetrahydroberberine) is a naturally occurring isoquinoline alkaloid, acting as a D2 receptor antagonist and 5-HT1A receptor agonist, capable of blocking dopamine-stimulated adenylate cyclase activity. (S) - (-) -Canadine also enhances gastrointestinal motility, blocks K (ATP) channels in substantia nigra pars compacta (SNc) dopaminergic neurons, and exerts neuroprotective effects.
Smiles
O(C)C1=C2CN3[C@](C=4C(=CC5=C(C4)OCO5)CC3)(CC2=CC=C1OC)[H]
Molecular Formula
C20H21NO4
Molecular Weight
339.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
TRC-C175175-100MGCanadine
166367S- (-) -Canadine
TRC-C175170-1G(R)-(+)-Canadine
FAA09657-01(S) - (-) -Canadine
sc-504595(R) - (+) -Canadine
TRC-C175180-25MG(S)-(-)-Canadine
TRC-C175177-25MGCanadine-d3 Hydrochloride
C175160(S)-(-)-Canadine Di-p-toluoyl-D-tartrate
sc-504594(S) - (-) -Canadine Di-p-toluoyl-D-tartrate
166368S- (-) -Canadine Di-p-toluoyl-D-tartrate

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