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Broussonin A

CAT: 0931-TN3539Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN3539Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
73731-87-0
Target
NOS, Akt, IκB/IKK, Cholinesterase (ChE), NF-κB, IL Receptor, ERK
Related Pathways
Neuroscience, NF-κB, MAPK, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Immunology/Inflammation
Bioactivity
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, transcriptional activity of estrogen-responsive element-luciferase reporter genes. Broussonin A can significantly inhibit adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay; it suppresses lipopolysaccharide (LPS) -stimulated inducible nitric oxide synthase (iNOS) expression at the transcriptional level through modulating NF-ÎoB and down-regulation of the Akt and ERK signaling pathways.
Smiles
COc1ccc(CCCc2ccc(O)cc2)c(O)c1
Molecular Formula
C16H18O3
Molecular Weight
258.317
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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A24104-50Broussonin E 50mg

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