Broussonin A

• CAS Number :

  73731-87-0

• Target :

  NOS|||Akt|||I?B/IKK|||Cholinesterase (ChE) |||NF-?B|||IL Receptor|||ERK

• Related Pathways :

  Neuroscience|||NF-?B|||MAPK|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Immunology/Inflammation

• Bioactivity :

  Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, transcriptional activity of estrogen-responsive element-luciferase reporter genes. Broussonin A can significantly inhibit adipocyte differentiation in 3T3-L1 cells as measured fat accumulation using Oil Red O assay; it suppresses lipopolysaccharide (LPS) -stimulated inducible nitric oxide synthase (iNOS) expression at the transcriptional level through modulating NF-κB and down-regulation of the Akt and ERK signaling pathways.

• Smiles :

  COc1ccc(CCCc2ccc(O)cc2)c(O)c1

• Molecular Formula :

  C16H18O3

• Molecular Weight :

  258.317

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C