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Aphadilactone C

CAT: 0931-TN3428Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-TN3428Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1522004-70-1
Target
Parasite|||Others|||Acyltransferase
Related Pathways
Microbiology/Virology|||Metabolism|||Others
Bioactivity
Aphadilactone C shows significant antimalarial activity with the IC50 value of 170 ± 10 nM. It shows potent and selective inhibition against the diacylglycerol O-acyltransferase-1 (DGAT-1) enzyme (IC50 = 0.46 ± 0.09 uM, selectivity index > 217) .
Smiles
C\C(CCC[C@H]1CC[C@](CCC\C(C)=C\[C@@H]2CC(C)=CC(=O)O2)(C2=CC(=O)C(C)(C)O2)C2=C1OC(C)(C)C2=O)=C/[C@@H]1CC(C)=CC(=O)O1
Molecular Formula
C40H52O8
Molecular Weight
660.84
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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