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Akuammigine

CAT: 0931-TN3368Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-TN3368Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
642-17-1
Target
Adrenergic Receptor, Opioid Receptor
Related Pathways
Endocrinology/Hormones, Neuroscience, GPCR/G Protein
Bioactivity
Akuammigine has in vitro antimalarial activity. Akuammigine competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding pA2 values of 4.68. Akuammidine also shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 microM at mu-, delta- and kappa-opioid binding sites, respectively.
Smiles
COC(=O)C1=CO[C@@H](C)[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@H]12
Molecular Formula
C21H24N2O3
Molecular Weight
352.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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