7,8-Didehydrocimigenol

• Target:

  TNF|||PPAR|||Akt|||NF-?B|||I?B/IKK|||ERK

• Related Pathways:

  Cytoskeletal Signaling|||NF-?B|||PI3K/Akt/mTOR signaling|||Apoptosis|||Metabolism|||MAPK|||DNA Damage/DNA Repair

• Bioactivity:

  7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-? in EC inhibits NF-kB activity of TNF-?-activated EC which leads to selective inhibition of VCAM-1 expression.

• Smiles:

  [H][C@]12[C@H] (C) C[C@H]3O[C@@]1 (O[C@@H]3C (C) (C) O) [C@H] (O) [C@@]1 (C) C3=CC[C@]4 ([H]) [C@]5 (C[C@@]35CC[C@]21C) CC[C@H] (O) C4 (C) C |t:20|

• Molecular Formula:

  C30H46O5

• Molecular Weight:

  486.693

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  150972-72-8