Products for Research Use Only

Sophoflavescenol

CAT: 0931-TN2217Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-TN2217Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
216450-65-6
Target
Beta-Secretase, Cholinesterase (ChE), BACE, PDE, AChR
Related Pathways
Metabolism, Neuroscience
Purity
0.9965
Bioactivity
Sophoflavescenol is a mixed inhibitor of PDE5 with a K (i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity without severe side effects. Sophoflavescenol exerts notable anti-inflammatory activity by inhibiting nitric oxide generation and tert-butylhydroperoxide-induced ROS generation rather than inhibiting nuclear factor kappa B activation in RAW 264.7 cells.
Smiles
COc1cc(O)c(CC=C(C)C)c2oc(c(O)c(=O)c12)-c1ccc(O)cc1
Molecular Formula
C21H20O6
Molecular Weight
368.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C