Saikogenin D

CAT: 0931-TN2169-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TN2169-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
5573-16-0
Target
Prostaglandin Receptor|||Potassium Channel|||IL Receptor|||Calcium Channel
Related Pathways
GPCR/G Protein|||Metabolism|||Membrane transporter/Ion channel|||Immunology/Inflammation
Purity
0.9999
Bioactivity
Saikogenin D possesses dual mechanisms of action including inhibition of A23187-induced PGE2 production without direct cyclooxygenase suppression, and stimulation of intracellular calcium elevation through Ca2+ release from internal stores, while further displaying immunomodulatory properties demonstrated by its ability to attenuate IL-6 production in LPS-stimulated alveolar macrophages from B6 mice more strongly than in BALB mice, highlighting selective regulation of inflammatory responses.
Smiles
C[C@]12[C@@]3(C)C(=C4[C@@](CO)([C@H](O)C3)CCC(C)(C)C4)C=C[C@@]1([C@]5(C)[C@@](CC2)([C@@](CO)(C)[C@@H](O)CC5)[H])[H]
Molecular Formula
C30H48O4
Molecular Weight
472.7
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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