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Pinoresinol

CAT: 0931-TN2080-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN2080-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
487-36-5
Target
CDK, p53, Apoptosis, NF-κB
Related Pathways
Apoptosis, NF-κB, Cell Cycle/Checkpoint
Purity
0.9867
Bioactivity
Pinoresinol ((+) -Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution; it may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.elegans. Pinoresinol causes an upregulation of the CDK inhibitor p21 (WAF1/Cip1) both at mRNA and protein levels, inhibits NF-kappaB and activating protein 1 (AP-1) .
Smiles
[H][C@]12CO[C@H](c3ccc(O)c(OC)c3)[C@@]1([H])CO[C@@H]2c1ccc(O)c(OC)c1
Molecular Formula
C20H22O6
Molecular Weight
358.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C