Pimaric acid

• Target :

  MMP|||p38 MAPK|||NF-?B|||Apoptosis

• Related Pathways :

  Proteases/Proteasome|||NF-?B|||Apoptosis|||MAPK

• Purity :

  0.8

• Bioactivity :

  Pimaric acid is a naturally occurring resin acid identified in species such as Aralia cordata and various pine trees. Pimaric acid exerts anticancer effects through induction of endoplasmic reticulum stress, activation of caspase-dependent apoptosis, cell cycle arrest, and inhibition of cell migration in ovarian cancer cells. Additionally, pimaric acid suppresses mRNA expression, protein levels, and promoter activity of matrix metalloproteinase-9 (MMP-9) in TNF-?-stimulated human aortic smooth muscle cells (HASMCs), supporting its role in cancer and vascular research.

• Smiles :

  [H][C@]12CC[C@@](C)(C=C)C=C1CC[C@@]1([H])[C@@](C)(CCC[C@]21C)C(O)=O

• Molecular Formula :

  C20H30O2

• Molecular Weight :

  302.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  127-27-5