Isosilybin A

• Target :

  NF-?B|||Apoptosis|||p38 MAPK|||Androgen Receptor|||ABC Transporter|||ERK|||PPAR|||Tyrosinase

• Related Pathways :

  NF-?B|||Endocrinology/Hormones|||DNA Damage/DNA Repair|||Membrane transporter/Ion channel|||MAPK|||Apoptosis|||Metabolism|||Proteases/Proteasome

• Purity :

  0.9988

• Bioactivity :

  Isosilybin A is a partial PPAR? agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6?M) and diphenolase (IC50=12.1-44.9?M) of tyrosinase. Isosilybin A shows anti-angiogenic efficacy, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction.

• Smiles :

  COc1cc(ccc1O)[C@H]1Oc2ccc(cc2O[C@@H]1CO)[C@H]1Oc2cc(O)cc(O)c2C(=O)[C@@H]1O

• Molecular Formula :

  C25H22O10

• Molecular Weight :

  482.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  142796-21-2