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Gossypetin

CAT: 0931-TN1711-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN1711-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
489-35-0
Target
MAPK, MEK, p38 MAPK, Antioxidant, Antibacterial
Related Pathways
Oxidation-Reduction, Microbiology/Virology, MAPK
Purity
0.95
Bioactivity
Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects.It inhibits bone resorption by downregulating lysosomal caspase K activity and inducing autophagy-associated proteins in actin ring osteoclasts. Gossypetin has anti-mutagenic, anti-atherosclerotic, anti-oxidant, cytoprotective and antibacterial effects, and it inhibits bone resorption by down-regulating lysosomal caspase K activity and by inducing autophagy-associated protein in actin ring osteoblasts.
Smiles
Oc1ccc(cc1O)-c1oc2c(O)c(O)cc(O)c2c(=O)c1O
Molecular Formula
C15H10O8
Molecular Weight
318.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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