Gossypetin

• Target:

  MAPK|||MEK|||p38 MAPK|||Antioxidant|||Antibacterial

• Related Pathways:

  Oxidation-Reduction|||Microbiology/Virology|||MAPK

• Purity:

  0.95

• Bioactivity:

  Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects.It inhibits bone resorption by downregulating lysosomal caspase K activity and inducing autophagy-associated proteins in actin ring osteoclasts. Gossypetin has anti-mutagenic, anti-atherosclerotic, anti-oxidant, cytoprotective and antibacterial effects, and it inhibits bone resorption by down-regulating lysosomal caspase K activity and by inducing autophagy-associated protein in actin ring osteoblasts.

• Smiles:

  Oc1ccc(cc1O)-c1oc2c(O)c(O)cc(O)c2c(=O)c1O

• Molecular Formula:

  C15H10O8

• Molecular Weight:

  318.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  489-35-0