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Astringin

CAT: 0931-TN1412-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TN1412-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
29884-49-9
Target
Ferroptosis, Akt, NF-κB, MyD88, PI3K, TLR
Related Pathways
Cytoskeletal Signaling, Apoptosis, NF-κB, PI3K/Akt/mTOR signaling, Immunology/Inflammation
Purity
0.9987
Bioactivity
Astringin (trans-Astringin) is an orally active natural flavonoid that mitigates oxidative stress and inflammatory responses by inhibiting the PI3K/AKT/NF-κB pathway. It also modulates TLR4/MyD88, HMGB1/RAGE, and NF-κB pathways to counteract chromium-induced nephrotoxicity, whilst inhibiting ferroptosis.
Smiles
O([C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C2=CC(/C=C/C3=CC(O)=C(O)C=C3)=CC(O)=C2
Molecular Formula
C20H22O9
Molecular Weight
406.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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