3-O-Methylgallic acid

CAT: 0931-TN1237-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0931-TN1237-01Size:100 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

3934-84-7

Target

Apoptosis, NF-κB, Caspase, STAT, OCT, DNA/RNA Synthesis

Related Pathways

NF-κB, Cell Cycle/Checkpoint, Stem Cells, Proteases/Proteasome, Apoptosis, JAK/STAT signaling, DNA Damage/DNA Repair, Membrane transporter/Ion channel

Purity

0.9956

Bioactivity

3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells (IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. It inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1, which are known to be activated in colorectal cancer.

Smiles

COc1cc(cc(O)c1O)C(O)=O

Molecular Formula

C8H8O5

Molecular Weight

184.15

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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3-O-Methylgallic acid

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