7-Hydroxyaristolochic acid A

CAT:
931-TN1004-01
Size:
1 mg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
7-Hydroxyaristolochic acid A - image 1

7-Hydroxyaristolochic acid A

  • Target:

    DNA/RNA Synthesis
  • Related Pathways:

    DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
  • Purity:

    0.9947
  • Bioactivity:

    7-Hydroxyaristolochic acid A is a natural derivative of aristolochic acid. Aristolochic acid is nephrotoxic and carcinogenic, inhibits APE1/Nrf2/HO-1 axis-induced oxidative stress and apoptosis leading to nephrotoxicity, and induces apoptosis in NRK-52E cells via COX-2 and PGE2.
  • Smiles:

    O=C (C1=CC2=C (C3=C4C=CC (O) =C (C4=CC ([N+] ([O-]) =O) =C13) OC) OCO2) O
  • Molecular Formula:

    C17H11NO8
  • Molecular Weight:

    357.27
  • Shipping Conditions:

    Cool pack
  • Storage Temperature:

    -20°C
  • CAS Number:

    79185-75-4