7-Hydroxyaristolochic acid A

CAT: 0931-TN1004-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-TN1004-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

79185-75-4

Target

DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

Purity

0.9947

Bioactivity

7-Hydroxyaristolochic acid A is a natural derivative of aristolochic acid. Aristolochic acid is nephrotoxic and carcinogenic, inhibits APE1/Nrf2/HO-1 axis-induced oxidative stress and apoptosis leading to nephrotoxicity, and induces apoptosis in NRK-52E cells via COX-2 and PGE2.

Smiles

O=C(C1=CC2=C(C3=C4C=CC(O)=C(C4=CC([N+]([O-])=O)=C13)OC)OCO2)O

Molecular Formula

C17H11NO8

Molecular Weight

357.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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7-Hydroxyaristolochic acid A

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