Ganoderiol F

• Target:

  Autophagy|||HIV Protease|||Androgen Receptor

• Related Pathways:

  Endocrinology/Hormones|||Proteases/Proteasome|||Autophagy|||Microbiology/Virology

• Bioactivity:

  Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC (50) values of 20-40 microM. It induced HO-1 expression, activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 and suppressed lipopolysaccharide (LPS) -induced nitric oxide (NO) production.

• Smiles:

  C[C@]12C=3C([C@]4(C)[C@@](CC3)(C(C)(C)C(=O)CC4)[H])=CC[C@]1(C)[C@@]([C@@H](CCC=C(CO)CO)C)(CC2)[H]

• Molecular Formula:

  C30H46O3

• Molecular Weight:

  454.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  114567-47-4