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Ganoderiol F

CAT: 0931-TMA1012-01Size: 500 µgDry Ice: NoHazardous: No
CAT#: TMA1012-01Size: 500 µg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
114567-47-4
Target
Autophagy|||HIV Protease|||Androgen Receptor
Related Pathways
Endocrinology/Hormones|||Proteases/Proteasome|||Autophagy|||Microbiology/Virology
Bioactivity
Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC (50) values of 20-40 microM. It induced HO-1 expression, activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 and suppressed lipopolysaccharide (LPS) -induced nitric oxide (NO) production.
Smiles
C[C@]12C=3C([C@]4(C)[C@@](CC3)(C(C)(C)C(=O)CC4)[H])=CC[C@]1(C)[C@@]([C@@H](CCC=C(CO)CO)C)(CC2)[H]
Molecular Formula
C30H46O3
Molecular Weight
454.68
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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