2,5-Dihydroxyacetophenone

• Target :

  Tyrosinase|||NF-?B|||ERK

• Related Pathways :

  NF-?B|||MAPK|||Proteases/Proteasome

• Purity :

  0.9991

• Bioactivity :

  1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPKs, it also can potentiate the pro-apoptotic and anti-proliferative effects of bortezomib in U266 cells. 3. 2,5-Dihydroxyacetophenone (Quinacetophenone) has anti-inflammatory activity in activated macrophages, raising the possibility that this compound has a therapeutic potential for inflammatory conditions. 4. 2,5-Dihydroxyacetophenone (Quinacetophenone) is an uncompetitive inhibitor of murine tyrosinase (K (I) 0.28mm), it strongly inhibits both melanogenesis and cellular tyrosinase activity in vitro in 3-isobutyl-1-methylxanthin-stimulated B16 mouse melanoma cells or in vivo in zebrafish and mouse models.

• Smiles :

  CC(=O)C1=CC(O)=CC=C1O

• Molecular Formula :

  C8H8O3

• Molecular Weight :

  152.15

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  490-78-8