EZM0414

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9958

• Bioactivity:

  EZM0414 is a potent and selective, orally bioavailable inhibitor of SETD2 with an IC50 of 18 nM in biochemical assays and 34 nM in cellular assays, potentially useful for researching relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma [1].

• Smiles:

  [H][C@@]1(CCC[C@H](C1)NC(=O)c1cc2c(F)ccc(C)c2[nH]1)N1CCN(CC1)C(C)=O

• Molecular Formula:

  C22H29FN4O2

• Molecular Weight:

  400.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2411748-50-8