NGD-8243

CAT: 0931-T9818-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T9818-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

573678-04-3

Target

TRP/TRPV Channel

Related Pathways

Membrane transporter/Ion channel

Purity

0.9526

Bioactivity

NGD-8243 (N-[4- (trifluoromethyl) phenyl]-7-[3- (trifluoromethyl) pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for prevention and treatment of cardiac hypertrophy.

Smiles

FC(F)(F)C1=CC=C(NC2=C3C=CC(=CC3=NC=N2)C2=C(C=CC=N2)C(F)(F)F)C=C1

Molecular Formula

C21H12F6N4

Molecular Weight

434.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Ngd-8243

CAS Number	573678-04-3
PubChem CID	11247522
IUPAC Name	N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)-2-pyridinyl]quinazolin-4-amine
Molecular Formula	C21H12F6N4
Molecular Weight	434.3
XLogP	5.8
Topological Polar Surface Area	50.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	3
Heavy Atom Count	31
Formal Charge	0
Complexity	589

SMILES

C1=CC(=C(N=C1)C2=CC3=C(C=C2)C(=NC=N3)NC4=CC=C(C=C4)C(F)(F)F)C(F)(F)F

InChI

InChI=1S/C21H12F6N4/c22-20(23,24)13-4-6-14(7-5-13)31-19-15-8-3-12(10-17(15)29-11-30-19)18-16(21(25,26)27)2-1-9-28-18/h1-11H,(H,29,30,31)

InChIKey

VTANGSDRFFLTSQ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 573678-04-3

CID: 11247522

Formula: C21H12F6N4

MW: 434.3

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	434.3
XLogP3	5.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	3
Exact Mass	434.09661537
Monoisotopic Mass	434.09661537
Topological Polar Surface Area	50.7 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	589
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Catalog	Name
MBS3617425-01	NGD-8243
HY-100318-01	NGD-4715
460709-01	NGD 94-1
BUA32270-01	NGD 4715
MBS5811923	NGD 98-2
A12461-100	NGD-4715 100mg
A12461-5	NGD-4715 5mg
A12461-1	NGD-4715 1mg
MBS5757539	NGD 98-2 hydrochloride
A12461-50	NGD-4715 50mg

NGD-8243

Chemical Information

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