IC 86621

• Target :

  DNA-PK|||Apoptosis

• Related Pathways :

  Apoptosis|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

• Purity :

  0.9968

• Bioactivity :

  IC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break (DSB) -induced antitumor activity with an EC50 of 68 µM for DNA-PK mediated cellular DSB repair.

• Smiles :

  CC(=O)c1ccc(cc1O)N1CCOCC1

• Molecular Formula :

  C12H15NO3

• Molecular Weight :

  221.25

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  404009-40-1