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Aplidine

CAT: 0931-T9715-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9715-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
137219-37-5
Target
DNA/RNA Synthesis, SARS-CoV
Related Pathways
Microbiology/Virology, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9986
Bioactivity
Aplidine possesses antiviral activity against SARS-CoV-2 (IC90 = 0.88 nM) . Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2 (EEF1A2, Kd = 80 nM) .
Smiles
[H][C@@]12CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)C(=O)[C@@H](OC(=O)C[C@H](O)[C@]([H])(NC(=O)[C@@H](NC(=O)[C@@H](CC(C)C)N(C)C(=O)[C@@H]1CCCN1C(=O)C(C)=O)[C@@H](C)OC(=O)[C@H](Cc1ccc(OC)cc1)N(C)C2=O)[C@@H](C)CC)C(C)C
Molecular Formula
C57H87N7O15
Molecular Weight
1110.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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